{"id":549562,"date":"2025-05-21T10:00:00","date_gmt":"2025-05-21T14:00:00","guid":{"rendered":"https:\/\/www.mdbriefcase.com\/postcall-item\/%f0%9f%a9%ba-a-dream-drug-with-side-effects\/"},"modified":"2025-05-21T10:00:00","modified_gmt":"2025-05-21T14:00:00","slug":"%f0%9f%a9%ba-a-dream-drug-with-side-effects","status":"publish","type":"postcall","link":"https:\/\/www.mdbriefcase.com\/fr\/postcall-item\/%f0%9f%a9%ba-a-dream-drug-with-side-effects\/","title":{"rendered":"\ud83e\ude7a A dream drug \u2014 with side effects"},"content":{"rendered":"<p><!DOCTYPE html><html><head><link href='https:\/\/fonts.gstatic.com' rel='preconnect'><link href='https:\/\/fonts.googleapis.com\/css2?family=Outfit&#038;display=swap' rel='stylesheet'><link href='https:\/\/fonts.googleapis.com\/css2?family=Inter&#038;display=swap' rel='stylesheet'><link href='https:\/\/fonts.googleapis.com\/css2?family=Open+Sans&#038;display=swap' rel='stylesheet'>\n<style type='text\/css'>\n:root {\n  --wt-primary-color: 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class='rendered-post' style='max-width: 672px; margin: 0 auto;'>\n<div class='bg-wt-background text-wt-text-on-background'>\n<div style='padding-top:1.5rem; padding-bottom:1.5rem;'>\n<style>\n  .bh__byline_wrapper {\n    font-size: .875rem;\n    line-height: 1.25rem;\n    vertical-align: middle;\n    justify-content: space-between;\n    display: block;\n  }<\/p>\n<p>  .bh__byline_social_wrapper {\n    display: flex;\n    margin-top: 0.5rem;\n    align-items: center;\n  }<\/p>\n<p>  .bh__byline_social_wrapper > * + * {\n    margin-left: 0.5rem;\n  }<\/p>\n<p>  @media (min-width: 768px) {\n    .bh__byline_wrapper {\n      display: flex;\n    }<\/p>\n<p>    .bh__byline_social_wrapper {\n      margin-top: 0rem;\n    }\n  }\n<\/style>\n<div id='web-header' style='padding-left: 15px; padding-right: 15px; color: var(--wt-text-on-background-color) !important; padding-bottom: 2rem;'>\n<h1 style='font-size: 36px; font-family:&#39;Trebuchet MS&#39;,&#39;Lucida Grande&#39;,Tahoma,sans-serif; line-height: 2.5rem; padding-bottom: 8px; font-weight: 700;'>\ud83e\ude7a A dream drug \u2014 with side effects<\/h1>\n<h2 style='font-size: 20px; font-family:&#39;Helvetica&#39;,Arial,sans-serif; line-height: 1.75rem; padding-bottom: 20px; font-weight: 400;'>PLUS: CRISPR in action, medical AI\u2019s new report card, and 55,000 postal workers ready to walk<\/h2>\n<div class='bh__byline_wrapper'>\n<div>\n<div style='display:flex;'>\n<div style='display:flex; flex-direction:row; justify-content:flex-start;'>\n<div style='display:flex;'><\/div>\n<div style='display:flex; align-items:center;'>\n<p style='left:24px;position:relative;font-family:&#39;Helvetica&#39;,Arial,sans-serif;font-weight:normal;font-size:14px;color: var(--wt-text-on-background-color);margin:0px;line-height:20px;'><span class='text-wt-text-on-background' style='opacity:0.75;'> May 21, 2025 <\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class='bh__byline_social_wrapper'><a 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src=\"https:\/\/media.beehiiv.com\/cdn-cgi\/image\/fit=scale-down,format=auto,onerror=redirect,quality=80\/uploads\/asset\/file\/cb78e1bc-d675-44f5-a0bc-648507a59463\/postcall_newsletter_header_with_border.png?t=1714495914\"\/><\/div>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"><b>Good morning!<\/b><\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"> This week: <span style=\"color:rgb(0, 0, 0);font-weight:400;\">CRISPR therapies, medical AI benchmarks, and another looming Canada Post strike \u2014 proof that medicine may move fast, but life still delivers on its own schedule. <\/span>\ud83d\ude9a <\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"><span style=\"text-decoration:underline;\">Today\u2019s issue takes 4 minutes to read<\/span>. Only got one? Here\u2019s what to know: <\/p>\n<\/div>\n<div style=\"padding-bottom:12px;padding-left:37px;padding-right:27px;padding-top:12px;\">\n<ul style=\"color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;list-style-type:disc;margin:0px 0px 0px 25px;padding:0;\">\n<li style=\"margin:10px 0px 0px 0px;\">\n<p style=\"text-align:left;\"> Amiloride matched spironolactone for resistant hypertension. <\/p>\n<\/li>\n<li style=\"margin:10px 0px 0px 0px;\">\n<p style=\"text-align:left;\"> Oveporexton improved narcolepsy symptoms, but caused insomnia. <\/p>\n<\/li>\n<li style=\"margin:10px 0px 0px 0px;\">\n<p style=\"text-align:left;\"> Vitamin D linked to lower risk of neurodevelopmental disorders. <\/p>\n<\/li>\n<li style=\"margin:10px 0px 0px 0px;\">\n<p style=\"text-align:left;\"> Gene editing helped infant with rare metabolic condition. <\/p>\n<\/li>\n<li style=\"margin:10px 0px 0px 0px;\">\n<p style=\"text-align:left;\"> Medical AI tool HealthBench evaluates GPT with real cases. <\/p>\n<\/li>\n<li style=\"margin:10px 0px 0px 0px;\">\n<p style=\"text-align:left;\"> Diet quality tied to timing of first periods. <\/p>\n<\/li>\n<\/ul>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"> Let\u2019s get into it. <\/p>\n<\/div>\n<div style=\"background-color:#23335E;border-bottom-left-radius:0px;border-bottom-right-radius:0px;border-bottom-width:0px;border-color:#222222;border-left-width:1px;border-right-width:1px;border-style:solid;border-top-left-radius:10px;border-top-right-radius:10px;border-top-width:1px;margin:7.0px 7.0px 0.0px 7.0px;padding:5.0px 5.0px 5.0px 5.0px;\">\n<div style=\"padding-bottom:4px;padding-left:15px;padding-right:15px;padding-top:16px;\">\n<h1 style=\"color:#2A2A2A;font-family:'Trebuchet MS','Lucida Grande',Tahoma,sans-serif;font-size:28px;font-weight:normal;line-height:42px;margin:0;text-align:left;\"><span style=\"color:#F9FAFB;\">Staying #Up2Date <\/span>\ud83d\udea8<\/h1>\n<\/div>\n<\/div>\n<div style=\"background-color:transparent;border-bottom-left-radius:10px;border-bottom-right-radius:10px;border-color:#222222;border-style:solid;border-top-left-radius:0px;border-top-right-radius:0px;border-width:1px;margin:0.0px 7.0px 14.0px 7.0px;padding:7.0px 7.0px 7.0px 7.0px;\">\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"><b>1: Pressure Tested: Amiloride for Resistant Hypertension<\/b><\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"> This <a class=\"link\" href=\"https:\/\/jamanetwork.com\/journals\/jama\/article-abstract\/2834040?utm_source=postcall.ca&#038;utm_medium=newsletter&#038;utm_campaign=a-dream-drug-with-side-effects\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\">RCT<\/a> explored amiloride as a potential alternative to spironolactone for treating resistant hypertension in 118 patients. After 12 weeks, amiloride lowered SBP by 13.6 mmHg (SD, 8.5) and showed equal efficacy to spironolactone, supporting its use as a viable treatment option.\u00a0 <\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"><b>2: Dream Drug for Narcolepsy?<\/b><\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"> This <a class=\"link\" href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2405847?utm_source=postcall.ca&#038;utm_medium=newsletter&#038;utm_campaign=a-dream-drug-with-side-effects\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\">phase-2 study<\/a><i>\u00a0<\/i>evaluated daily oveporexton for 90 patients with narcolepsy type 1. After 8 weeks, oveporexton significantly improved wakefulness, reduced sleepiness, and reduced cataplexy compared to placebo. However, side effects were notable: 48% reported insomnia and 33% reported urinary urgency.\u00a0 <\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"><b>3: A Dose of Sunshine!\u00a0<\/b><\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"> This Danish <a class=\"link\" href=\"https:\/\/www.thelancet.com\/journals\/lanpsy\/article\/PIIS2215-0366(25)00099-9\/abstract?utm_source=postcall.ca&#038;utm_medium=newsletter&#038;utm_campaign=a-dream-drug-with-side-effects\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\">population study <\/a>of over 80K individuals examined links between vitamin D status and mental health outcomes. Higher 25 hydroxyvitamin D levels were associated with lower risks of\u00a0schizophrenia (HR 0.82, 95% CI 0.78\u20130.86), ADHD (HR 0.89, 95% CI 0.86\u20130.92), and ASD (HR 0.93, 95% CI 0.90\u20130.96). These findings suggest that optimization of neonatal vitamin D could help lower the incidence of neurodevelopmental disorders. <\/p>\n<\/div>\n<\/div>\n<div style=\"background-color:#23335E;border-bottom-left-radius:0px;border-bottom-right-radius:0px;border-bottom-width:0px;border-color:#222222;border-left-width:1px;border-right-width:1px;border-style:solid;border-top-left-radius:10px;border-top-right-radius:10px;border-top-width:1px;margin:7.0px 7.0px 0.0px 7.0px;padding:5.0px 5.0px 5.0px 5.0px;\">\n<div style=\"padding-bottom:4px;padding-left:15px;padding-right:15px;padding-top:16px;\">\n<h1 style=\"color:#2A2A2A;font-family:'Trebuchet MS','Lucida Grande',Tahoma,sans-serif;font-size:28px;font-weight:normal;line-height:42px;margin:0;text-align:left;\"><span style=\"color:#F9FAFB;\">A Rare Win <\/span>\ud83e\uddec<\/h1>\n<\/div>\n<\/div>\n<div style=\"background-color:transparent;border-bottom-left-radius:10px;border-bottom-right-radius:10px;border-color:#222222;border-style:solid;border-top-left-radius:0px;border-top-right-radius:0px;border-width:1px;margin:0.0px 7.0px 14.0px 7.0px;padding:7.0px 7.0px 7.0px 7.0px;\">\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"><i>Scientists&#39; latest breakthrough could change how we think about genetic diseases<\/i><\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"><b>What happened: <\/b>A baby born with a rare and deadly genetic disease is given another chance thanks to an experimental <a class=\"link\" href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2504747?utm_source=postcall.ca&#038;utm_medium=newsletter&#038;utm_campaign=a-dream-drug-with-side-effects\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\">gene editing treatment<\/a> made just for him. <\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"><b>Why it matters: <\/b>The patient had a <a class=\"link\" href=\"https:\/\/www.cbc.ca\/news\/health\/gene-therapy-baby-pennsylvania-1.7536105?utm_source=postcall.ca&#038;utm_medium=newsletter&#038;utm_campaign=a-dream-drug-with-side-effects\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\">CPS1 deficiency<\/a>, a tiny error in his genetic code that affects the body\u2019s ability to break down protein and remove nitrogen waste. It can cause dangerously high ammonia levels\u00a0and is fatal in about half of all diagnosed infants. <\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"> Doctors at the Philadelphia Children\u2019s Hospital spent 6 months designing a treatment to correct the faulty gene. Using CRISPR, they flipped the mutated DNA base back to its correct form, reducing the risk of unwanted genetic changes. The therapy was delivered via IV using\u00a0lipid nanoparticles \u2014 tiny fatty droplets absorbed by liver cells. After <a class=\"link\" href=\"https:\/\/www.cbc.ca\/news\/health\/gene-therapy-baby-pennsylvania-1.7536105?utm_source=postcall.ca&#038;utm_medium=newsletter&#038;utm_campaign=a-dream-drug-with-side-effects\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\">2 follow-up doses<\/a>, the patient began eating normally, recovering from illnesses more quickly and needing\u00a0less medication.\u00a0 <\/p>\n<\/div>\n<div style=\"padding-left:15px;padding-right:15px;\">\n<div style=\"padding-bottom:20px;padding-left:0px;padding-right:0px;padding-top:20px;\"><img decoding=\"async\" alt=\"\" style=\"margin:0 auto 0 auto;width:70%;\" src=\"https:\/\/media.beehiiv.com\/cdn-cgi\/image\/fit=scale-down,format=auto,onerror=redirect,quality=80\/uploads\/asset\/file\/84d1c661-6400-4332-a806-d5e00bde606a\/sangharsh-lohakare-8o_LkMpo8ug-unsplash.jpg?t=1747754123\"\/><\/div>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"><b>But: <\/b>It\u2019s still early \u2014 doctors say it could take years of follow-up to know if the results hold. <\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"> Researchers hope to learn from this case and eventually apply the knowledge to other rare diseases. While gene therapy can be expensive, they noted the cost wasn\u2019t far off from an <a class=\"link\" href=\"https:\/\/www.cbc.ca\/news\/health\/gene-therapy-baby-pennsylvania-1.7536105?utm_source=postcall.ca&#038;utm_medium=newsletter&#038;utm_campaign=a-dream-drug-with-side-effects\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\">average liver transplant<\/a> \u2014 and future therapies could become cheaper as methods become more efficient.\u00a0 <\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"><b>Bottom line: <\/b>Personalized medicine just might be the future \u2014 and breakthroughs like this remind us how powerful science can be.\u00a0 <\/p>\n<\/div>\n<\/div>\n<div style=\"background-color:#23335E;border-bottom-left-radius:0px;border-bottom-right-radius:0px;border-bottom-width:0px;border-color:#222222;border-left-width:1px;border-right-width:1px;border-style:solid;border-top-left-radius:10px;border-top-right-radius:10px;border-top-width:1px;margin:7.0px 7.0px 0.0px 7.0px;padding:5.0px 5.0px 5.0px 5.0px;\">\n<div style=\"padding-bottom:4px;padding-left:15px;padding-right:15px;padding-top:16px;\">\n<h1 style=\"color:#2A2A2A;font-family:'Trebuchet MS','Lucida Grande',Tahoma,sans-serif;font-size:28px;font-weight:normal;line-height:42px;margin:0;text-align:left;\"><span style=\"color:#F9FAFB;\">Hot Off The Press<\/span><\/h1>\n<\/div>\n<\/div>\n<div style=\"background-color:transparent;border-bottom-left-radius:10px;border-bottom-right-radius:10px;border-color:#222222;border-style:solid;border-top-left-radius:0px;border-top-right-radius:0px;border-width:1px;margin:0.0px 7.0px 14.0px 7.0px;padding:7.0px 7.0px 7.0px 7.0px;\">\n<div style=\"padding-left:15px;padding-right:15px;\">\n<div style=\"padding-bottom:20px;padding-left:0px;padding-right:0px;padding-top:20px;\"><img decoding=\"async\" alt=\"\" style=\"margin:0 auto 0 auto;width:70%;\" src=\"https:\/\/media.beehiiv.com\/cdn-cgi\/image\/fit=scale-down,format=auto,onerror=redirect,quality=80\/uploads\/asset\/file\/c80cd7fc-aaa8-4cfc-bf3b-59248205dab0\/levart_photographer-7q-kE4SZzvQ-unsplash.jpg?t=1747755853\"\/><\/div>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"> 1: \ud83e\udd16 OpenAI\u2019s new tool, <a class=\"link\" href=\"https:\/\/www.mobihealthnews.com\/news\/openai-unveils-healthbench-evaluate-llms-safety-healthcare?utm_source=postcall.ca&#038;utm_medium=newsletter&#038;utm_campaign=a-dream-drug-with-side-effects\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\">HealthBench<\/a>, puts medical AI to the test \u2014 literally. It uses 5,000 synthetic doctor-patient conversations, each graded by physicians using custom rubrics, to see how well models like GPT can handle real clinical questions. The goal: figure out not just what AI gets right, but where it might quietly fail. <\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"> 2: \ud83e\udd57\u00a0<a class=\"link\" href=\"https:\/\/academic.oup.com\/humrep\/advance-article\/doi\/10.1093\/humrep\/deaf072\/8125832?login=false&#038;utm_source=postcall.ca&#038;utm_medium=newsletter&#038;utm_campaign=a-dream-drug-with-side-effects#google_vignette\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\">New research<\/a> links diet quality to the timing of first periods. In a long-term US study, girls who ate healthier diets hit menarche a bit later \u2014 while those with more inflammatory diets hit it earlier. The link held even after adjusting for BMI and height, hinting that what kids eat might play a bigger role in puberty than we thought. <\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"> 3: \ud83d\udc43\u00a0<a class=\"link\" href=\"https:\/\/www.nature.com\/articles\/s41590-025-02156-0?utm_source=postcall.ca&#038;utm_medium=newsletter&#038;utm_campaign=a-dream-drug-with-side-effects\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\">A new study in mice<\/a> shows that a nasal COVID booster \u2014 with no added immune stimulants \u2014 can still trigger a strong local immune response. The secret? Prior vaccination seems to &quot;prep&quot; the immune system, letting the nasal dose recruit memory cells to the lungs. It\u2019s early, but researchers say it could pave the way for safer, most effective intranasal vaccines. <\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"> 4: \ud83d\udcec Canada Post workers are <a class=\"link\" href=\"https:\/\/www.canadapost-postescanada.ca\/cpc\/en\/our-company\/news-and-media\/corporate-news\/negotiations\/2025-05-19-canada-post-receives-strike-notices-from-cupw-customers-should-be-prepared-for-possible-service-delays?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\">planning to strike<\/a> \u2014 again. 55,000 postal workers are set to walk off the job as early as 12:01 a.m. on Friday. It&#39;s their second walkout in 6 months, with the union citing overwork, job insecurity, and wage gaps. Expect delivery delays if talks stall. <\/p>\n<\/div>\n<\/div>\n<div style=\"background-color:#23335E;border-bottom-left-radius:0px;border-bottom-right-radius:0px;border-bottom-width:0px;border-color:#222222;border-left-width:1px;border-right-width:1px;border-style:solid;border-top-left-radius:10px;border-top-right-radius:10px;border-top-width:1px;margin:7.0px 7.0px 0.0px 7.0px;padding:5.0px 5.0px 5.0px 5.0px;\">\n<div style=\"padding-bottom:4px;padding-left:15px;padding-right:15px;padding-top:16px;\">\n<h1 style=\"color:#2A2A2A;font-family:'Trebuchet MS','Lucida Grande',Tahoma,sans-serif;font-size:28px;font-weight:normal;line-height:42px;margin:0;text-align:left;\"><span style=\"color:#F9FAFB;\">Notable Numbers <\/span>\ud83d\udd22<\/h1>\n<\/div>\n<\/div>\n<div style=\"background-color:transparent;border-bottom-left-radius:10px;border-bottom-right-radius:10px;border-color:#222222;border-style:solid;border-top-left-radius:0px;border-top-right-radius:0px;border-width:1px;margin:0.0px 7.0px 14.0px 7.0px;padding:7.0px 7.0px 7.0px 7.0px;\">\n<div style=\"padding-left:15px;padding-right:15px;\">\n<div style=\"padding-bottom:20px;padding-left:0px;padding-right:0px;padding-top:20px;\"><img decoding=\"async\" alt=\"\" style=\"margin:0 auto 0 auto;width:60%;\" src=\"https:\/\/media.beehiiv.com\/cdn-cgi\/image\/fit=scale-down,format=auto,onerror=redirect,quality=80\/uploads\/asset\/file\/7e182153-70b6-4e7f-9d23-2cdb6c8f3547\/erik-mclean-4ACaUyPyjoY-unsplash.jpg?t=1747750689\"\/><\/div>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"><b>$80 million<\/b>: how much a man from Surrey, BC, recently claimed in the <a class=\"link\" href=\"https:\/\/ici.radio-canada.ca\/rci\/en\/news\/2165604\/b-c-winner-of-record-80m-lottery-jackpot-quits-job-vows-to-give-back-to-community?utm_source=postcall.ca&#038;utm_medium=newsletter&#038;utm_campaign=a-dream-drug-with-side-effects\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\">largest single payout<\/a> in Canadian lottery history. Justin Simporios says he plans to help his sister pay off her medical school debt and give back to his community. <\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"><b>3 weeks: <\/b>how long siblings Lilly (6) and Jack (4) Sullivan <a class=\"link\" href=\"https:\/\/www.cbc.ca\/news\/canada\/nova-scotia\/experts-point-to-anomalies-in-unprecedented-case-of-missing-ns-children-1.7536905?utm_source=postcall.ca&#038;utm_medium=newsletter&#038;utm_campaign=a-dream-drug-with-side-effects\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\">have been missing<\/a> from their rural Nova Scotia home. Despite hundreds of tips and renewed search efforts, no trace has been found. Experts call the case \u201cunprecedented,\u201d pointing to the total lack of evidence and deviation from typical missing children investigations. <\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"><b>27%:<\/b> how many migraine patients avoided fatigue by taking ubrogepant before the headache hit, <a class=\"link\" href=\"https:\/\/www.nature.com\/articles\/d41586-025-01503-3?utm_source=postcall.ca&#038;utm_medium=newsletter&#038;utm_campaign=a-dream-drug-with-side-effects#:~:text=Results%20from%20a%20phase%20III,headache%20fatigue%20and%20light%20sensitivity\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\">compared to 17% on placebo<\/a>. Researchers say it\u2019s the first drug shown to ease non-pain symptoms in the early phase of a migraine, including dizziness, neck pain, and light sensitivity. <\/p>\n<\/div>\n<\/div>\n<div style=\"background-color:#23335E;border-bottom-left-radius:0px;border-bottom-right-radius:0px;border-bottom-width:0px;border-color:#222222;border-left-width:1px;border-right-width:1px;border-style:solid;border-top-left-radius:10px;border-top-right-radius:10px;border-top-width:1px;margin:7.0px 7.0px 0.0px 7.0px;padding:5.0px 5.0px 5.0px 5.0px;\">\n<div style=\"padding-bottom:4px;padding-left:15px;padding-right:15px;padding-top:16px;\">\n<h1 style=\"color:#2A2A2A;font-family:'Trebuchet MS','Lucida Grande',Tahoma,sans-serif;font-size:28px;font-weight:normal;line-height:42px;margin:0;text-align:left;\"><span style=\"color:#F9FAFB;\">Picks<\/span><\/h1>\n<\/div>\n<\/div>\n<div style=\"background-color:transparent;border-bottom-left-radius:10px;border-bottom-right-radius:10px;border-color:#222222;border-style:solid;border-top-left-radius:0px;border-top-right-radius:0px;border-width:1px;margin:0.0px 7.0px 14.0px 7.0px;padding:7.0px 7.0px 7.0px 7.0px;\">\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"> \ud83d\ude02<b>Laugh: <\/b>at this meme about a hard day&#39;s work: <\/p>\n<\/div>\n<div style=\"padding-left:15px;padding-right:15px;\">\n<div style=\"padding-bottom:20px;padding-left:0px;padding-right:0px;padding-top:20px;\"><img decoding=\"async\" alt=\"\" style=\"margin:0 auto 0 auto;width:65%;\" src=\"https:\/\/lh7-rt.googleusercontent.com\/docsz\/AD_4nXfS8_AGxgn_RhL88VdsADwJ7aByLMDaIE-fjdDohmwVbbWk0831KBQ7ZLoeVcFCpw8j4OAh9ickiUfzZyyawCdEW_5AKipn0uPQOBnTGcl1XspZl4TOb5p70I_aih9Pl1E1C-Z6?key=r3IKEF13Es5k2Jea_XHAW9LN\"\/><\/div>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"> \ud83c\udfa7<b> Listen: <\/b>to <a class=\"link\" href=\"https:\/\/www.cbc.ca\/radio\/whitecoat\/seasonal-allergies-getting-worse-1.7537006?utm_source=postcall.ca&#038;utm_medium=newsletter&#038;utm_campaign=a-dream-drug-with-side-effects\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\">this timely episode of <\/a><i><a class=\"link\" href=\"https:\/\/www.cbc.ca\/radio\/whitecoat\/seasonal-allergies-getting-worse-1.7537006?utm_source=postcall.ca&#038;utm_medium=newsletter&#038;utm_campaign=a-dream-drug-with-side-effects\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\">White Coat, Black Art<\/a><\/i> on seasonal allergies, exploring how climate change is making symptoms worse, and what new sublingual immunotherapies could do to help. <\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"> \ud83e\udd11<b>Save &#8211; <\/b>Samsung Canada is currently offering <a class=\"link\" href=\"https:\/\/www.samsung.com\/ca\/offer\/?utm_source=postcall.ca&#038;utm_medium=newsletter&#038;utm_campaign=a-dream-drug-with-side-effects\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\">up to 30% off for verified medical professionals<\/a> through their Education &#038; Employee Purchase Program (EPP). It includes phones, tablets, and monitors \u2014 perfect for clinic or call-room upgrades. <\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"><b>\u270d\ufe0fRegister: <\/b>for a virtual evening with <a class=\"link\" href=\"https:\/\/www.oma.org\/news\/events\/doctors-lounge-an-evening-with-dr.-christopher-booth?utm_source=postcall.ca&#038;utm_medium=newsletter&#038;utm_campaign=a-dream-drug-with-side-effects\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\">Dr. Paul Newhouse<\/a>. Learn about the clinical use of nicotine and how you might be underprescribing it. <\/p>\n<\/div>\n<\/div>\n<div style=\"background-color:#23335E;border-bottom-left-radius:0px;border-bottom-right-radius:0px;border-bottom-width:0px;border-color:#222222;border-left-width:1px;border-right-width:1px;border-style:solid;border-top-left-radius:10px;border-top-right-radius:10px;border-top-width:1px;margin:7.0px 7.0px 0.0px 7.0px;padding:5.0px 5.0px 5.0px 5.0px;\">\n<div style=\"padding-bottom:4px;padding-left:15px;padding-right:15px;padding-top:16px;\">\n<h1 style=\"color:#2A2A2A;font-family:'Trebuchet MS','Lucida Grande',Tahoma,sans-serif;font-size:28px;font-weight:normal;line-height:42px;margin:0;text-align:left;\"><span style=\"color:#F9FAFB;\">Relax<\/span><\/h1>\n<\/div>\n<\/div>\n<div style=\"background-color:transparent;border-bottom-left-radius:10px;border-bottom-right-radius:10px;border-color:#222222;border-style:solid;border-top-left-radius:0px;border-top-right-radius:0px;border-width:1px;margin:0.0px 7.0px 14.0px 7.0px;padding:7.0px 7.0px 7.0px 7.0px;\">\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"><b>First Question<\/b>: Specialty with a Mohs micrographic surgery fellowship <\/p>\n<\/div>\n<div style=\"padding-left:15px;padding-right:15px;\">\n<div style=\"padding-bottom:20px;padding-left:0px;padding-right:0px;padding-top:20px;\"><a href=\"https:\/\/postcall.ca\/p\/postcall-crossword-may-21\" rel=\"nofollow noopener noreferrer\" style=\"text-decoration: none;\" target=\"_blank\"><img decoding=\"async\" alt=\"\" style=\"margin:0 auto 0 auto;width:45%;\" src=\"https:\/\/media.beehiiv.com\/cdn-cgi\/image\/fit=scale-down,format=auto,onerror=redirect,quality=80\/uploads\/asset\/file\/e06e8d57-f235-4783-922e-1b64643df780\/image.png?t=1747708953\"\/><\/a><\/p>\n<div style=\"margin:0 auto 0 auto;padding-left:0px;padding-right:0px;padding-top:4px;text-align:center;width:45%;\"><a href=\"https:\/\/postcall.ca\/p\/postcall-crossword-may-21\" rel=\"noopener\" style=\"color:#000000;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:12px;font-style:italic;text-decoration-color:#000000;text-decoration:underline;\" target=\"_blank\"><\/p>\n<p>Give it a go \u2192<\/p>\n<p><\/a><\/div>\n<\/div>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"><b>Need a rematch?<\/b> We\u2019ve got you covered. <b>Check out <\/b><b><a class=\"link\" href=\"https:\/\/postcall.ca\/c\/crosswords\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" style=\"-webkit-text-decoration:underline #2C81E5;color:#3f72af;font-style:italic;text-decoration:underline #2C81E5;word-break:break-word;;\"><span style=\"color: rgba(var(--sk_highlight,18,100,163),1)\">our Crossword Archive<\/span><\/a><\/b> \u2014 find <i>every<\/i> puzzle we\u2019ve ever made, all in one place. <\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"> If you enjoyed the puzzle, challenge your physician friends and see if they can beat your time. <\/p>\n<\/div>\n<\/div>\n<div style=\"background-color:#23335E;border-bottom-left-radius:0px;border-bottom-right-radius:0px;border-bottom-width:0px;border-color:#222222;border-left-width:1px;border-right-width:1px;border-style:solid;border-top-left-radius:10px;border-top-right-radius:10px;border-top-width:1px;margin:7.0px 7.0px 0.0px 7.0px;padding:5.0px 5.0px 5.0px 5.0px;\">\n<div style=\"padding-bottom:4px;padding-left:15px;padding-right:15px;padding-top:16px;\">\n<h1 style=\"color:#2A2A2A;font-family:'Trebuchet MS','Lucida Grande',Tahoma,sans-serif;font-size:28px;font-weight:normal;line-height:42px;margin:0;text-align:left;\"><span style=\"color:#F9FAFB;\">Share Postcall, Get Rewards<\/span><\/h1>\n<\/div>\n<\/div>\n<div style=\"background-color:transparent;border-bottom-left-radius:10px;border-bottom-right-radius:10px;border-color:#222222;border-style:solid;border-top-left-radius:0px;border-top-right-radius:0px;border-width:1px;margin:0.0px 7.0px 14.0px 7.0px;padding:7.0px 7.0px 7.0px 7.0px;\"><\/div>\n<div style=\"background-color:#23335E;border-bottom-left-radius:0px;border-bottom-right-radius:0px;border-bottom-width:0px;border-color:#222222;border-left-width:1px;border-right-width:1px;border-style:solid;border-top-left-radius:10px;border-top-right-radius:10px;border-top-width:1px;margin:7.0px 7.0px 0.0px 7.0px;padding:5.0px 5.0px 5.0px 5.0px;\">\n<div style=\"padding-bottom:4px;padding-left:15px;padding-right:15px;padding-top:16px;\">\n<h1 style=\"color:#2A2A2A;font-family:'Trebuchet MS','Lucida Grande',Tahoma,sans-serif;font-size:28px;font-weight:normal;line-height:42px;margin:0;text-align:left;\"><span style=\"color:#F9FAFB;\">Help Us Get Better<\/span><\/h1>\n<\/div>\n<\/div>\n<div style=\"background-color:transparent;border-bottom-left-radius:10px;border-bottom-right-radius:10px;border-color:#222222;border-style:solid;border-top-left-radius:0px;border-top-right-radius:0px;border-width:1px;margin:0.0px 7.0px 14.0px 7.0px;padding:7.0px 7.0px 7.0px 7.0px;\">\n<table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" role=\"presentation\" style=\"border-collapse:collapse;\" width=\"100%\">\n<tr>\n<td align=\"left\" style=\"padding:15px 15px 12px;\">\n<h3 style=\"color:var(--wt-text-on-background-color);font-family:'Trebuchet MS','Lucida Grande',Tahoma,sans-serif;font-size:20px;font-weight:normal;line-height:30px;margin:0;text-align:left;\">What&#39;d you think of today&#39;s edition?<\/h3>\n<\/td>\n<\/tr>\n<tr>\n<td align=\"left\" style=\"font-size:.75rem;line-height:1rem;opacity:.75;padding:0px 15px 15px;text-align:left;\">\n<div style=\"padding-bottom:12px;padding-left:0px;padding-right:0px;padding-top:12px;\">\n<ul style=\"color:var(--wt-text-on-background-color);font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;list-style-type:none;margin-left:0px;margin:0;padding:0;\">\n<li style=\"color:var(--wt-text-on-background-color);font-style:italic;text-decoration-color:#2C81E5;text-decoration:underline;\"><a data-skip-tracking=\"true\" rel=\"noopener noreferrer nofollow\" style=\"color:inherit;\" target=\"_blank\" href=\"https:\/\/postcall.ca\/polls\/60959914-723b-4f30-86d7-c110bee66815\/response?pcid=46560186-e77d-486a-acad-e8ee1e53042a&#038;ppid=20ef0876-9787-4816-a47b-184e46103f44&#038;sid=SUBSCRIBER_ID\"> \u2b50\u2b50\u2b50\u2b50\u2b50 &#8211; Lit up my day. <\/a><\/li>\n<li style=\"color:var(--wt-text-on-background-color);font-style:italic;text-decoration-color:#2C81E5;text-decoration:underline;\"><a data-skip-tracking=\"true\" rel=\"noopener noreferrer nofollow\" style=\"color:inherit;\" target=\"_blank\" href=\"https:\/\/postcall.ca\/polls\/60959914-723b-4f30-86d7-c110bee66815\/response?pcid=58ede54f-b349-43bd-8a41-1534c2be27ac&#038;ppid=20ef0876-9787-4816-a47b-184e46103f44&#038;sid=SUBSCRIBER_ID\"> \u2b50\u2b50\u2b50 &#8211; It was alright. <\/a><\/li>\n<li style=\"color:var(--wt-text-on-background-color);font-style:italic;text-decoration-color:#2C81E5;text-decoration:underline;\"><a data-skip-tracking=\"true\" rel=\"noopener noreferrer nofollow\" style=\"color:inherit;\" target=\"_blank\" href=\"https:\/\/postcall.ca\/polls\/60959914-723b-4f30-86d7-c110bee66815\/response?pcid=b3a11ad5-c118-4878-8be0-68441a62d7e3&#038;ppid=20ef0876-9787-4816-a47b-184e46103f44&#038;sid=SUBSCRIBER_ID\"> \u2b50 &#8211; Boo, bring it harder next time. <\/a><\/li>\n<\/ul>\n<\/div>\n<\/td>\n<\/tr>\n<\/table>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"> That\u2019s all for this issue. <\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"> Cheers, <\/p>\n<\/div>\n<style>\n  p span[style*=\"font-size\"] { line-height: 1.6; }\n<\/style>\n<div style=\"padding-bottom:12px;padding-left:15px;padding-right:15px;padding-top:12px;\">\n<p style=\"color:#2D2D2D;color:var(--wt-text-on-background-color) !important;font-family:'Helvetica',Arial,sans-serif;font-size:16px;line-height:24px;text-align:left;\"> The Postcall team. <\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p><\/body><\/html><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\ud83e\ude7a A dream drug \u2014 with side effects PLUS: CRISPR in action, medical AI\u2019s new report card, and 55,000 postal workers ready to walk May 21, 2025 Good morning! This week: CRISPR therapies, medical AI benchmarks, and another looming Canada Post strike \u2014 proof that medicine may move fast, but life still delivers on its [&hellip;]<\/p>\n","protected":false},"author":15405,"featured_media":549563,"menu_order":0,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[],"tags":[639],"class_list":["post-549562","postcall","type-postcall","status-publish","has-post-thumbnail","hentry","tag-api-import"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\ud83e\ude7a A dream drug \u2014 with side effects - MDBriefCase<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.mdbriefcase.com\/fr\/postcall-item\/\ud83e\ude7a-a-dream-drug-with-side-effects\/\" \/>\n<meta property=\"og:locale\" content=\"fr_CA\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\ud83e\ude7a A dream drug \u2014 with side effects - MDBriefCase\" \/>\n<meta property=\"og:description\" content=\"\ud83e\ude7a A dream drug \u2014 with side effects PLUS: CRISPR in action, medical AI\u2019s new report card, and 55,000 postal workers ready to walk May 21, 2025 Good morning! 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