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A free online accredited CPD program for healthcare professionals

The Future is Here: Pharmacogenomics (PGx) and Personalized Medicine in Primary Care

1.00 Mainpro+ Credit(s)

Program available online until: August 24, 2018

This Self-Learning program has been certified by the College of Family Physicians of Canada for up to 1.00 Mainpro+ Credit(s).

Pharmacogenomics and Personalized Medicine in Primary Care


This eCME is directed to primary care clinicians (family physicians, nurse practitioners and pharmacists) in the therapeutic area of pharmacogenetic testing and personalized medicine. This one-hour program will be accredited through the CFPC and CCCEP.

Pharmacogenomics (PGx) focuses on understanding how genes affect individual responses to medications, i.e., the relationship between drug responses and genetic variants.PGx testing provides objective data about specific aspects of an individual’s genetic makeup that may predict an individual’s response to medications. For example, the liver enzyme CYP2D6 is involved in metabolizing a quarter of all prescriptions, and exists in more than 160 known variants. Some variants can negatively impact how particular drugs are metabolized by individuals who carry the variants.

This program will highlight implications of PGx testing that apply specifically to the primary care setting, and provide information on common scenarios to prepare the primary care clinician to effectively incorporate PGx testing into practice when appropriate.

Planning Committee

  • Daniel Ngui, MD, CCFP, FCFP.
  • John Papastergiou, BScPhm.
  • Moe Abdallah, BSc, BScPhm, RPh.
  • Daniel J Mueller, MD, PhD.
  • Deanna Telner, MD, CFPC, FCFP.
  • John Axler, MD, FCFP, CCFP.

Learning Objectives

Upon completion of this program, participants will be able to:

  1. Define pharmacogenetics/pharmacogenomics and personalized medicine;
  2. Describe how you might counsel patients about the potential benefits and risks of pharmacogenomic testing;
  3. Review clinically relevant examples of pharmacogenetics and explain how knowledge of the genetics of an individual’s metabolism may impact choice and/or dosage of medications;
  4. Discuss common and relevant genetic variants that can be identified through genetic testing that impact clinical decision-making in the primary care setting to improve patient outcomes.

Questions answered by our experts: Daniel J Mueller, MD, PhD and
John Papastergiou, BSc Phm, RPh

  • What are the key milestones in the past few years that make PGx testing feasible in primary care now?
  • Considering that these tests are still new, and other than situations such as pregnancy and cancer, what are the situations for which primary care clinicians might counsel their patients for about any genetic testing?
  • What do you feel are the benefits of genetic testing pertinent to primary care? How do you explain these benefits to patients in a way that they can understand?
  • What are some clinical risk factors that genetic testing might be useful for particular patients? How do you explain these risks to patients in a way they can understand?
  • Which therapeutic areas benefit most from genetic testing pertinent to primary care?
  • What are the key elements you include when you discuss pharmacogenomics and genetic testing with your patients? Do you have any handouts or guidelines to support this discussion?

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